Flexeril Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing
The use of significant lower dosing schedules in elderly patients may be prudent. Older adults may be more sensitive to the side effects of this drug, especially drowsiness, confusion, constipation, or trouble urinating. Drowsiness and confusion can increase the risk of falling. Before taking cyclobenzaprine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
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Skeletal muscle relaxants are widely used in treating musculoskeletal conditions. However, evidence of their effectiveness consists mainly of studies with poor methodologic design. In addition, these drugs have not been proven to be superior to acetaminophen or nonsteroidal anti-inflammatory drugs for low back pain. Systematic reviews and meta-analyses support using skeletal muscle relaxants for short-term relief of acute low back pain when nonsteroidal anti-inflammatory drugs or acetaminophen are not effective or tolerated.
Selection of a skeletal muscle relaxant should be individualized to the patient. If there are tender spots over the muscle or trigger points on physical examination, a skeletal muscle relaxant is a reasonable adjunct to analgesic treatment of low back pain. Skeletal muscle relaxants may also be used as an alternative to NSAIDs in patients who are at risk of gastrointestinal or renal complications.
- While the maximum dose of Cyclobenzaprine is 3 X 10mg daily, it is not advised to take this dose at once, or even 2 x 10mg in one dose.
- Hyperpyretic crisis seizures, and deaths have occurred in patients receiving cyclobenzaprine (or structurally similar tricyclic antidepressants) concomitantly with MAO inhibitor drugs.
- To help avoid interactions, your doctor should manage all of your medications carefully.
- For the most part, Flexeril doesn’t produce a euphoric high.
- The plasma concentration of cyclobenzaprine is increased in patients with hepatic impairment (see CLINICAL PHARMACOLOGY, Pharmacokinetics, Hepatic Impairment).
More common side effects
This means your doctor will need to get approval from your insurance company before your insurance company will pay for the prescription. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription.
In particular, the prevalence of daytime drowsiness was lower with evening bedtime VLD CBP, at 22% of patients, vs 34% reported in a study in FM patients with higher daytime dosages (up to 40 mg) of CBP2. Our study was designed to investigate the effects of bedtime dosing of VLD CBP (≤ 4 mg/day) in subjects with FM and disrupted sleep. It was also designed to identify variables that might be useful markers of drug effects. The rationale for the study was that bedtime administration of VLD CBP would have a more acceptable side effect profile than higher doses administered during the day2,3,4,5,6,7,8, and yet might show effects on FM symptoms. Both cyclobenzaprine and methocarbamol have depressive effects on the central nervous system and can interact with other drugs that have a similar effect, such as benzodiazepines, opiate pain medications, and antidepressants. When these drugs interact, it can worsen side effects like drowsiness and dizziness.
However, doctors don’t typically prescribe Flexeril alone. It is generally used alongside physical therapy and rest. Adverse events (AE) were recorded at all study visits or as they occurred. Blood chemistry tests (including thyroid-stimulating hormone at screening only), hematology tests, and urinalysis were performed at screening and on Days −1 and 56.
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If you experience these adverse effects, please seek emergency medical attention. Some people prefer Fexmid and Amrix over Robaxin because it is dosed once a day rather than 3 to 4 times a day. On the other hand, they can cause more adverse effects such as dry mouth and drowsiness. Taking Flexeril in the recommended dosage and for the right length of time is flexeril bad for the kidneys should pose little to no risk of dependence or addiction forming. Abusing the drug in higher doses or combining it with other central nervous system depressants like benzodiazepines increases the risk of addiction as well as the potential for overdose. Cyclobenzaprine relieves skeletal muscle spasm of local origin without interfering with muscle function.
Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your care team if the problem does not go away or is severe. Talk to your care team about the use of this medication in children. If this medication upsets your stomach, take it with food or milk.
Generally, young adults ages 18 to 25 misuse Flexeril at higher rates than other age groups. This may be the result of the availability of information on Flexeril. Because of the internet, people can find out the desirable effects of Flexeril.